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Acute symptoms such as fatigue may improve relatively quickly, whereas neurological symptoms like paraesthesia (pins and needles) or cognitive difficulties typically require longer treatment courses

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As a result, TNF- orchestrates a process of local (expressed as bone erosions and juxta-articular osteoporosis) and systemic bone loss in patients with inflammatory arthritis [12, 35, 36]

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Vitamin D has multiple functions related to musculoskeletal health and helps regulate inflammatory processes