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Raymond-Delpech V, Matsuda K, Sattelle BM, Rauh JJ, Sattelle DB

They appear to depend mainly on carbohydrates as their energy source and for that reason are thought to have a much higher number of insulin receptors on their surface

References 1 Medicine PCotASfR

1992 Ouichou

Slightly positive or near-neutral zeta potentials (approximately 10 to +10 mV) are generally preferred for systemic administration because highly cationic particles can strongly bind to the negatively charged endothelial glycocalyx and plasma proteins, causing aggregation, complement activation, and membrane damage (120)