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We first examined whether MIEAP, a molecule involved in noncanonical mitophagy, and ATG5, a component of autophagic machinery and involved in canonical mitophagy, are tumor suppressors in thyroid carcinogenesis using genetically engineered mice and found that thyroid cancer development was accelerated in Braf thyrV600E ,Atg5 thyrKO/KO and Braf thyrV600E ,Mieap KO/KO mice compared with Braf thyrV600E mice

The combination of baicalin and baicalein enhances apoptosis via the ERK/p38 MAPK pathway in human breast cancer cells

Cryo-EM structure of the human chemerin receptor 1Gi protein complex bound to the C-terminal nonapeptide of chemerin

Primary intracellular antioxidant that maintains cellular redox balance