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Although SASP contributes markedly to inflammaging, its effect is not limited to this, but is of a complex pleiotropic nature, which has been explained in detail in the recent review by Birch and Gil [46]

418 Collectively, these factors critically limit the application of TCM in the management of diabetic complications

pylori infection [23], chronic atrophic gastritis [78], unhealthy diets [129] and inheritance [22] et al

Depressive-like symptoms are exacerbated by activation of P2X 7 R in glial cells

It also reduced UVB-induced inflammation and DNA damage, while promoting skin hydration and reducing melanin productionkey factors in diminishing wrinkle formation (133)