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In research models it readily crosses the blood-brain barrier and influences several physiological processes beyond just sleep

These include age, overall health status, specific health goals, and whether its being used topically or systemically

Causes of Compromised Immunity: Chronic stress, poor gut health (where 70% of your immune system resides), nutrient deficiencies, and lack of sleep

For patients whose goals are sleep, longevity, and cellular renewal, that is a remarkably light commitment relative to the depth of the mechanism it targets

Others describe difficulty sleeping, particularly with late-day injections