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(1983) examined the biochemical alterations in liver and blood, and the histological findings in the liver of female C57BL/6J mice after a single oral administration of carbon tetrachloride in liquid paraffin at doses of 0.02, 0.5 or 1.5 ml/kg body weight (calculated to be 32, 797 or 2391 mg/kg body weight) at various times from 15 to 327 h after administration

His-Tag Protease Contamination A non-obvious but well-documented mechanism

As for side effects, some individuals may experience side effects such as stomach upset or allergic reactions

Smith, D., M

doi: 10.1186/s13075-022-02852-4 98 ZhangWDohertyMBardinTPascualEBarskovaVConaghanPet al