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Following treatment and subsequent remission in patients, relapse of the disease is driven by this drug-resistant CD34 + CD38 - LSC fraction which has unlimited self-renewal capabilities (102)

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Ahlskog, J

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In contrast, CRISPR/Cas9 knockout of Drp1 has high specificity and basic research value, making it suitable for diseases that require long-term gene regulation

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Hepatology 42 , 317325 (2005)

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However, there was no appreciable effect on the upstream components of the STAT3 signaling pathway, such as JAK2 and p-JAK2 (Figure 4D)

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