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Ann Intern Med 166(3):191200 Rena G, Lang CC (2018) Repurposing metformin for cardiovascular disease

ROS-initiated chemiluminescence-driven payload release from macrocycle-based Azo-containing polymer nanocapsules

The most important serious side effects include acute pancreatitis (severe persistent abdominal pain radiating to the back, though clinical trials found similar pancreatitis rates to comparators), severe dehydration from persistent vomiting or diarrhea (signs include dizziness, decreased urination, extreme thirst), gallbladder disease including cholecystitis or cholelithiasis (right upper quadrant pain, fever, jaundice), severe allergic reactions (difficulty breathing, swelling of face or throat), and severe hypoglycemia when combined with insulin or sulfonylureas (confusion, loss of consciousness, seizures)

The role of senescence in late-stage therapy-resistant cancer is a major component of this research

Microbiota and kidney disease: the road ahead