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However, FDA has identified serious adverse events associated with CJC-1295 in available data, including increased heart rate and systemic vasodilatory reactions

[PMC free article] [PubMed] [Google Scholar] 229.Fernando W., Coyle K., Marcato P., Vasantha Rupasinghe H.P., Hoskin D.W

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After we performed a more unbiased assessment of polar localization over time that incorporates the entire population of cells rather than selection by eye (see Methods), it became evident that the R49Q mutant was indeed impaired in its ability to localize to the pole in comparison to wild-type ArqI (Fig