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Our previous studies have shown that injected mitochondria improve mitochondrial homeostasis and turnover by restoring dynamic mitochondrial protein loss in DA neurons, including increasing mitochondrial fusion-fission proteins and autophagy of damaged mitochondria in the SN 7

doi: 10.1038/nn.4475 57 SrinivasanKFriedmanBALarsonJLLaufferBEGoldsteinLDApplingLLet al

Larabi, for their help with protein expression, purification, crystallization and X-ray diffraction analyses

This differs from the process in yeast, where sulfide must be incorporated first in homocysteine then converted in two steps to cysteine

A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease