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Oxidative Stress and Diabetes Cardiovascular complications, characterized by endothelial dysfunction and accelerated atherosclerosis, are the leading cause of morbidity and mortality associated with diabetes (Salem et al ., 2009)

Using structural analysis, v6pep (KEQWFGNRWHEGYR) was selected from the human CD44v6 domain that interacts with c-Met and inhibits tumor growth and metastasis in a pancreatic cancer model 112,113

All viral mutants were amplified on complementing cell lines and titrated on Vero cells and compared to their respective wild-type viral strain

These established therapies should generally be considered first-line treatments unless contraindicated or ineffective for individual patients