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such alterations come from the innate and adaptive IS and melanocytes morphology and metabolism ( In 2007, alterations in the NALP1 genomic region were identified in vitiligo patients (Song et al., 2013) increases the incidence of APC antigen presentation and cytotoxic T cells activation via B7 (from APC) to CD28 cytotoxic T cell binding (Figure 1)

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10.1016/j.jid.2020.09.031 24 FloryS.SusN.HaasK.JehleS.KienhferE.WaehlerR.et al (2021)