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Carcinoma 10, 21732185

[DOI] [PubMed] [Google Scholar] 81.Xu M., Tchkonia T., Ding H., Ogrodnik M., Lubbers E.R., Pirtskhalava T., White T.A., Johnson K.O., Stout M.B., Mezera V., et al

After 24 h media was replaced by fresh medium and further incubated for 3 days

Impaired cell signaling pathways also disrupt this cycle, and once this happens, pigment can no longer be regenerated, leading to permanent greying

Other Nrf2-dependent genes, including GPX4, GSH and NADPH synthesis genes, as well as epigenetic regulators of lipid hydroperoxides, contribute to its ferroptosis-inhibitory effects (117119)