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Nat Rev Immunol 2006

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Multiple studies have found that ALI in sepsis patients can be significantly alleviated by inhibiting signaling pathways such as JNK and p38 MAPK (172, 178, 179)

Additionally, ferroptosis was found to occur in either plateau-type pulmonary oedema or paraquat-induced PF, whereas regulation of the Keap1/Nrf2/HO-1 pathway significantly upregulated ferroptosis-associated proteins and reversed ferroptosis [109, 111]