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[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Cauli A, Shaw J, Giles J, Hatano H, Rysnik O, Payeli S, McHugh K, Dessole G, Porru G, Desogus E, et al

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Additionally, inhibition of CD36 effectively decreased ceramide-induced JNK and p66Shc serine 36 phosphorylation, preserving mitochondrial function, enhancing antioxidant defenses (thioredoxin-2 and peroxiredoxin-3), and restoring GSIS, suggesting CD36 as a potential therapeutic target to mitigate ceramide-induced -cell dysfunction [9]

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