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Dopamine subsequently undergoes enzymatic inactivation catalyzed by MAO and catechol- O methyltransferase (COMT)

Moreover, certain naturally occurring polyphenolic compounds, such as quercetin, nifedipine, and procyanidin C1, have also demonstrated potent anti-senescence activity [194, 213]

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Based on individual gene expression results, aged sample replicates CMO303 (WT) and CMO306 ( Mda5 -/- ) were found to be unfit for further analysis and were excluded

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