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Xie M-Y, Huang G-L, Lin Z-Y, Sun X-F, Wu C-C, Liu Y-W, et al

2-[[(Cyclopropylamino)carbonyl]amino]-N-(2,6-dimethylphenyl)-6-benzothiazolecarboxamide

It is not a synthetic drug designed to block or force a single biological pathway

Natural polyphenolic compounds, including hesperidin (HP) and resveratrol, alleviate Cd-induced oxidative stress and synaptic impairment by reestablishing the GSH/non-protein thiol (NP-SH) balance, preventing lipid peroxidation (LPO) and protein carbonylation (PC), directly neutralizing reactive oxygen species (ROS), and improving cytochrome P450 enzymes to reduce neuronal apoptosis (158, 159)