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Particularly intriguing was the finding that mice treated with triple therapy had a complete absence of metastases as assessed by gross morphology as well as histological examination of extrapancreatic organs (Fig

Beyond TLR4/MyD88 inhibition, accumulating evidence indicates that dioscin exerts broader cytoprotective actions by attenuating oxidative stress and regulated cell death pathways, including ferroptosis, necroptosis, and apoptosis, through activation of Nrf2/HO-1 signaling, modulation of SIRT1/SIRT3-associated mitochondrial homeostasis, and suppression of inflammation-driven tubular injury (Zhang et al

SEC does, however, offer a quick and reliable method for removing salts or small molecules from a sample between early or intermediate stages of the purification

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