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Significance of the pleiotropic beneficial effects for Roberts concept (stomach cytoprotection/adaptative cytoprotection organoprotection) and Selyes stress coping response concept Of note, Roberts concept (stomach cytoprotection/adaptative cytoprotection organoprotection) on which more focus is put on may be more workable

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Considering that PDCs increased the local concentration of cytotoxic agents in tumor tissues, they can reduce cytotoxic effects to normal tissues and increase therapeutic efficacy

However, from a clinical application perspective, both techniques require expensive machines that take up a lot of space and require expertise