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Hence, it is critical to maintain physiologically relevant levels of intracellular ROS for health and longevity

Side Effects: See Figure 2

Administering 5 mg/kg/d intraperitoneally for 2 weeks, they observed significant improvements in cardiac function, including increased stroke volume (SV) and CO, and reduced left ventricular end-diastolic pressure (LVEDP), alongside elevated NRF2 expression and decreased oxidative stress in non-infarcted myocardium

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Long-duration tissue explant cultures , including bone explants and neural slice cultures, similarly benefit from extended ligand availability