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By activating the GABA B receptor, GABA inhibits GSK-3 activity, which enhances -catenin signaling, promoting cancer cell proliferation while suppressing intratumoral infiltration of CD8 + T cells

Conversely, the expression of the OLIGOPEPTIDE TRANSPORTER (OPT) and GAMMA-GLUTAMYL TRANSPEPTIDASE 1 (GGT1) genes, encoding proteins involved in transporting GSH to the apoplast and breaking down GSSG in the apoplast (Zhang et al., 2016