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Description

Upregulation of NLRP3 via STAT3-dependent histone acetylation contributes to painful neuropathy induced by bortezomib

doi: 10.3389/fphar.2026.1767206 Received 14 December 2025 Revised 01 June 2026 Accepted 08 June 2026 Published 30 June 2026 Volume 17 - 2026 Edited by Nidhi Jalan-Sakrikar, Mayo Clinic, United States Reviewed by Slaan Pavlovi, University of Belgrade, Serbia Uro akar, University of Belgrade, Serbia Seddik Hammad, Heidelberg University, Germany Updates Copyright 2026 Philips, Sreemohan, Baby, Theruvath, Oommen, Ahamed, Tharakan and Augustine

Lyophilized powder receives sterile water or bacteriostatic water through controlled syringe transfer into a sealed vial

The combination is safe and effective for Fitzpatrick III to V skin when the needle depth and session frequency are calibrated conservatively, and when the patient follows consistent sun protection