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Peroxiredoxin-2 is a redox protein that neutralizes H 2 O 2

Notably, the C-terminal FAP cleavage site remains unmodified, suggesting that LY2405319 is likely susceptible to cleavage and inactivation in human serum via loss affinity for KLB ( Figure 3A )

This suggests GLP-1 RAs may play a more direct role in testicular function than previously thought. Lets break it down further

This process removes intermediates from the TCA cycle which will potentially decrease the ability of the cycle to oxidize pyruvate and produce reducing equivalents for ETC and ATP synthesis