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When SLC7A11 is suppressed by erastin, the transsulfuration pathway is upregulated, which could block ferroptosis [51]

10.1007/s12640-016-9633-5 53

Finally, some people have genetic mutations which means they require more vitamin B12 than other

Beyond cystine uptake, the intracellular cysteine pool can be sustained by the transsulfuration pathway in the liver, although its contribution to other tissues is less clear (Combs and DeNicola, 2019)

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