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A study of the cerebral volume and induced stroke following middle cerebral artery occlusion in mice showed that HHcy was associated with increased oxidative damage and larger ischemic lesion [1719]

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Also, suppression of diacylglycerol acyltransferase 2 (DGAT2, an enzyme that catalyzes the final step of triglyceride synthesis from diacylglycerol) decreased hepatic DAG contents, reversed diet-induced hepatic steatosis and insulin resistance, and reduced PKC levels in plasma membranes [170]

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91 Another prospective study that followed nearly 55,000 people for 13 years found people with multiple insomnia-related symptoms had a higher risk of heart failure

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Discoveries in pharmacology

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