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Effector T cells abrogate stroma-mediated chemoresistance in ovarian cancer

(30), which used metformin as the control

Experimental data point oxidative stress as one of the factors that contributes to aquaporin-1 up-regulation since administration of the antioxidant melatonin not only reduced protein levels but also mechanical allodynia and appearance of aquaporin-1-positive fibers below laminae I and II (Nesic et al., 2008)