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The biggest cons of semaglutide for her are: Nausea Hyper-fixating on foods Receiving some backlash for taking the medication The nausea was "awful," Dunham said: "Not unmanageable, but not fun." By "hyper-fixating" on foods, Dunham means that if she feels she wants, say, McDonald's French fries, she's not satisfied and doesn't want to eat anything else until she's got them, she said