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J Taibah Univ Med Sci , 20 (3), 417428

10.1016/j.jprot.2011.08.007 68 JaumannM.DettlingJ.GubeltM.ZimmermannU.GerlingA.Paquet-DurandF.et al

These fatty acids are extremely susceptible to oxidative damage by free radicals or Reactive Oxygen Species (ROS) by a process called lipid peroxidation (LPO)

For this reason, numerous researchers have devoted themselves to developing melatonin sustained release delivery systems for the treatment of OA ( Figure 5 )

According to a study on oxidative stress in aging human skin, vitamin C has a significant role in various enzymatic reactions, including collagen cross-linking