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doi: 10.1189/jlb.1106672

The current medical treatment of choice for hypothyroidism is hormone replacement therapy with the drug levothyroxine (Synthroid [Knoll Pharm Co, Mt Olive, NJ]), which contains a synthetic version of T4

Thus, exposure of the brain to elevated homocysteine levels leads to overstimulation of NMDA receptors, oxidative stress, DNA damage, and endoplasmic and mitochondrial dysfunction, which may be responsible for some of the brain damage and neurodegeneration associated with AUD (26, 47)

Despite promising results, few direct comparisons exist between well-established pharmaceutical treatments and natural productexercise programs

J Neurochem 120:147156 Tinggi U (2008) Selenium: Its role as antioxidant in human health