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This interaction creates a glial activation loop that emphasises their mutual signalling and synergistic effects [89, 90]

Regeneration of Other Antioxidants : Glutathione helps recycle other antioxidants, such as vitamins C and E, thereby enhancing their effectiveness in combating oxidative stress

Org Agric 11:179185 [Google Scholar] Rawindran H, Khoo KS, Ethiraj B, Suparmaniam U, Leong WH, Raksasat R, Liew CS, Sahrin NT, Lam MK, Kiatkittipong W, Lim JW, Zango ZU, Shahid MK, Abdelghani HTM, Ng HS (2023) Fundamental alteration of cellular biochemicals from attached microalgae onto palm kernel expeller waste upon optimizing the growth environment in forming adhesion complex

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In particular, we aimed to assess the role of inflammation and oxidative stress with a focus on the nuclear factor-kappa B (NF-B), the Janus kinase/signal transducer and activator of the transcription3 (JAK/STAT3), nuclear factor erythroid-2-related factor 2/heme oxygenase-1 (Nrf2/HO-1), peroxisome proliferator-activated receptor-gamma (PPAR-), and silent information regulator-1 (SIRT1) in pathogenesis of intestinal injury induced by MTX