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FIGURE 2 TABLE 1 Regulation of p53 in ferroptosis network

660 Below we detail the sensing elements used in CFE diagnostics

Since the absorption and emission spectra of NADH and NADPH are almost the same due to the nicotinamide moieties, it is appropriate to refer to the ~350 nm-excited autofluorescence as NAD(P)H ( Figure 3 )

This iron-sequestering capability is particularly important because excess free iron directly enters cells, concentrates in mitochondria, disrupts oxidative phosphorylation, catalyzes lipid peroxidation, and ultimately leads to cell death

However, when the reoxygenation was extended for longer, cell repair started and ECD decreased [136]