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Nature Geoscience v

VDAC1 transferred via EVs induces PTX resistance siRNAs were used to silence the expression of VDAC1 protein in GC cells to further investigate the potential role of EV-derived VDAC1 protein in mediating intercellular drug resistance transmission

These free radicals are known to speed up aging and contribute to health issues like heart disease and even cancer

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In addition, most of the effective analgesics in NP failed to provide symptomatic relief of CIPN and often exhibit side effects (Han and Smith, In general, unlike other types of NP (including those induced by trauma and diabetes) axonal degeneration in peripheral nerves is not present in CIPN (Ji et al., Regarding to CIPN induced by the taxanes, Duggett et al