Thank you to our sponsors AG1 (Athletic Greens): InsideTracker: Thesis: Supplements from Momentous For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Introduction (00:04:15) The bedrock of sleep-rest cycles (00:07:05) Night owls and morning larks (00:08:22) The perfect schedule (00:11:04) The 100K Lux per morning goal (00:15:15) Keeping your biological clock set (00:16:15) Reset your cortisol (00:21:22) Jetlag, death and lifespan (00:23:00) Going East versus West (00:28:45) The key to clock control (00:31:01) Your Temperature Minimum (00:36:30) Temperature and Exercise (00:41:20) Eating (00:42:50) Go West (00:44:15) Pineal myths and realities (00:51:13) The Heat-Cold Paradox (00:53:45) Staying on track (00:55:30) Nightshades (00:57:00) Emergency resets (00:57:30) Psychosis by light (00:58:05) Shift work (01:02:40) The Temperature-Light Rule (01:04:20) Up all night: watch the sunrise
ROS production and AKT/PI3K
Administering sodium hydrosulfide (NaSH), at 2.8 mg/kg, once a day for 3 months ameliorated memory deficits, reduced APP and BACE1, upregulated the master regulator of antioxidant response genes, nuclear factor erythroid-2-related factor 2 (Nrf2), heme oxygenase-1(HO-1) and glutathione S-transferase (GST) in the APP/PS1 model of AD (Liu et al., 2 S donor, AP-39, maintained cellular bioenergetics and preserved mitochondrial function in the APP/PS1 mouse model of AD (Zhao et al., 2016)
A: Expect initial improvements in texture and radiance within 24 weeks
It also helps boost collagen production, shrink pores, smooth fine lines, and even tone the complexion
