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The biosynthesis of PC with different thiol residues can be from different pathways of sulfur metabolism recorded significant variation through the treatments

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After 48 h of treatment, BUTE cell-conditioned media (BUTE-CM) was collected from 1 to 6 flasks per technical replicate, depending on the number of EVs needed for subsequent analysis

Increased ROS production due to age-related dysregulation of CYPs contributes to DNA damage, protein oxidation, and lipid peroxidation all of which accelerate aging and trigger cellular senescence (Hamsanathan and Gurkar, 2022