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Description

Funding This work was supported by the key technology of preparation of Chinese herbal formula containing volatile oil and the support of industrialization research project (YDZX2021050)

Precise metabolomics reveals a diversity of aging-associated metabolic features

Keywords: Lipid metabolism, Insulin resistance, Dyslipidemia, Aging, Oxidative stress, GH/IGF-I axis, Obesity, Mitochondrial dysfunction, Cellular protection Background Consistent data from multiple studies (in vitro and in vivo) demonstrate the association between IGF-1 deficit and deregulated lipid metabolism, cardiovascular disease (CVD), diabetes, and altered metabolic profile of diabetic patients

Complementary DNA (cDNA) was synthesised using reverse transcriptase and random primers using a high-capacity cDNA Reverse Transcription Kit (Applied Biosystems, USA)