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The multi-class Receiver Operative Characteristics (ROC) curve, which represented the level of concordance between synthesized CBV and ground truth CBV, reached a sensitivity of 0.76 and a specificity of 0.89 at the operating point, and the area-under-the-curve (AUC) was 0.91 (Figure 6)

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Start Low, Go Slow: If a medical professional approves a combination, they would likely advise starting with low doses and gradually increasing, while carefully monitoring for any adverse reactions or unexpected effects