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We then tested whether other agents that specifically caused nucleotide imbalance (rather than the DNA-driven and RNA-driven effects of 5FU) have the same mechanism of action

Methods in Enzymology 391 (2005) 163-176

Mitoxantrone Theoretically, quercetin might increase the effects and adverse effects of mitoxantrone

This includes coordinated effects on both innate and adaptive responses and is mediated by engagement of key inflammatory and antioxidant signaling pathways (Figure 3)