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J Alzheimers Dis 2016;54:983-93

Hormone Replacement Therapy (HRT): The Stepwise Method Instead of jumping into full hormone replacement, McCall recommends a phased approach: Prioritize Based on Symptoms: Progesterone: For anxiety, insomnia, heavy periods, mood swings Testosterone: For low libido, energy issues, muscle loss Estrogen: Last to drop, often during peri/menopause Action Plan: Begin with the hormone causing the most distress

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Be alert to these supporting symptoms: Constant fatigue, even after good sleep Tingling or numbness in fingers and toes Poor memory or mental fog Mood swings or unexplained anxiety Muscle weakness Breathlessness or palpitations If your skin issues coincide with any of these , its a strong indicator that you should get your B12 levels tested