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NNMT inhibitors are selective and do not impact related methyltransferases or enzymes in the NAD + salvage pathway The selectivity of NNMT inhibitors was confirmed by testing against a panel of structurally similar methyltransferases and two enzymes in the NAD + salvage pathway (NAMPT and SIRT1

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This PCR product consists on a Kan resistance cassette (Kan R ), with FRT sites from pKD4, flanked by 40 bp identity arms to the genes of interest

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Ferritin is a blood protein that stores and releases iron into your body, which in turn supports several important processes