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Peptides such as GLP-1 and exenatide have been trialed in various contexts, predominantly for their involvement in weight control and type 2 diabetes

The rationale was that direct delivery to the joint would maximize local efficacy while minimizing systemic exposure

Vitamin B12 injections may help to: Increase energy levels and reduce fatigue Improve mental clarity, focus, and memory Boost mood and reduce feelings of anxiety or low mood Support a healthy metabolism and aid weight management Strengthen the immune system Improve sleep quality Promote healthy hair, skin, and nails Many clients report feeling a difference within just a few hours or days of their injection, especially if their levels were previously low

Because the injection allows for direct absorption, the effects are typically felt much more quickly than with oral supplements

They usually occur in the initial phase of starting the treatment or during dose escalation, but improve over time