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The entry of nanoparticles into solid tumours

Fabbro-Peray P, Zouaoui S, Darlix A, Fabbro M, Pallud J, Rigau V, et al

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By blocking the phosphorylation of Smad proteins, stachydrine reduces the expression of pro-fibrotic genes, thus diminishing the fibrotic response

Its unique mechanism, hypothesized to involve direct DNA interaction rather than surface receptor binding, sets it apart from other bioregulator peptides