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It is often controlled by addition of an internal standard at an early stage of sample preparations step

FMS prescribed Glutathione IV combined with chemical peels

& Schuster, J

We therefore propose that acidification of mutant supernatant (via secretion of acids and impaired urease activity) and changes to extracellular antioxidant composition circumvented the oxidation of L-DOPA, thereby preventing its use in melanin formation by gsh2 mutants