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The location of the parasite inside the phagolysosome is promoted by the presence of lipophosphoglycan (LPG) along the parasite surface (Moradin and Descoteaux, 2012

The intracellular redox state exists in a dynamic equilibrium [2], orchestrated by controlled reactive oxygen species (ROS) production and elimination [3, 4]

8 Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan

Proteomics of GAPDH knockdown and inhibition For proteomics of GAPDH KD and KA-treated cells, protein pellets upon methanol precipitation were also resuspended in 50% TFE/ABC and 20 g protein was further subjected to redox proteomics preparation as previously described

Importantly, the body weight of A375 tumor-bearing mice in both the MN-CCPCA and MN-CCPCA ( + ) groups was slightly increased during the treatment period (Supplementary Fig