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10.1111/bjh.17091 10

It is also essential for folate and related one-carbon metabolism, where FAD is required as a cofactor for methylenetetrahydrofolate reductase (MTHFR), a key folate-metabolizing enzyme

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Bauer JL, Kuhn K, Bradford AP, et al

Although Parkinsons data remain heterogeneous, small controlled studies indicate that multi-vitamin protocols combining riboflavin with other mitochondrial cofactors can dampen oxidative stress and improve motor scores, warranting standardized outcome frameworks before widespread adoption (6, 84)