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Specifically, murine systems lack the heterogeneous donor-recipient interactions, comorbidities (e.g., diabetes, hypertension), and immunosuppressive drug effects pervasive in clinical settings

Lyophilised peptides tolerate ambient temperature (up to 25C) for 24 weeks without significant degradation shipping at room temperature is acceptable for unreconstituted powder

J Neurosci 27, 16311641 (2007)

The majority of Treg cells express the CD25 molecule (IL-2R receptor), which exhibits a high affinity for IL-2 and initiates CD25-mediated signaling through activation of the transcription factor STAT5 [154]