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10.1097/CAD.0b013e32833db89d 77 KandaH.TateyaS.TamoriY.KotaniK.HiasaK.KitazawaR.et al (2006)

Lactobacillus murinus alleviate intestinal ischemia/reperfusion injury through promoting the release of interleukin-10 from M2 macrophages via Toll-like receptor 2 signaling

HMGB1 activates the NF-B pathway through TLR4/TLR2: in the lungs, it promotes the release of inflammatory factors, leading to acute lung injury

The 60 samples were processed in 5 batches of 12 (each time point had 6 controls and 6 cKOt mice), with each batch corresponding to a full time series for each genotype