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Among many other plant oxylipins, di- and trihydroxy-octadecanoids are synthesised in some plants, and 2-oxo-5,8,12-trihydroxy-dodecanoic acid was first found in bean seeds and has been shown to stimulate the growth of pea stem segments, to induce amylase synthesis in barley endosperm, and to retard senescence in barley leaf segments

Successful transplantation of human kidneys deemed untransplantable but resuscitated by ex vivo normothermic machine perfusion

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That lead to the conclusion that acute glutathione depletion may be involved

Metformin, as a ROS inhibitor, can maintain T cell activity by reducing intracellular ROS levels, thereby promoting tumor clearance and reducing tumor-associated inflammation [95]