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Description

Heme oxygenase-1 upregulation: a novel approach in the treatment of cardiovascular disease

NAD-BD and Glu-BD form the catalytic cleft

Nagy, P., Jameson, G

Carcinog 28 , 240245 (2007)

P53 phosphorylation at Ser15 enhances the affinity of both FOXO4 and FOXO4-DRI for p53 TAD2 explaining the preferential engagement of FOXO4-DRI with the hyperphosphorylated p53 characteristic of senescent cells