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doi: 10.1007/s00011-022-01672-1 104 MohrMELiSTroutenAMStairleyRARoddyPLLiuCet al

Interestingly, the addition of mevalonate rescues the LXR-mediated suppression of T-cell proliferation

Oxidative stress plays a prominent role in SARS-CoV-2 infection following recognition of the viral S-protein by angiotensin converting enzyme-2 receptor and pattern recognition receptors like toll-like receptors 2 and 4, and activation of transcription factors like nuclear factor kappa B, that subsequently activate nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) expression succeeded by ROS production

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