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Methods: The CDOCKER software was utilized to perform the insilico study and binding affinity of AUF with P13K alpha subunit (5DXT), AKT (1UNQ), GSK3 (1Q41), Nrf2 (2DYH), and HO1 (1N45) were estimated

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They not only directly inhibit tumor cell proliferation and induce apoptosis but also, more importantly, potently activate DCs, promoting their maturation and antigen-presenting function, thereby laying the foundation for cytotoxic T-cell activation [272,273,274,275]

Laboratory studies suggest the peptide can shift gene-expression patterns toward a profile associated with younger tissue and may support the activity of cells involved in repair

The contaminating genomic DNA was removed by digestion with the enzyme DNaseI (Epicentre Technologie, United States), free of RNase activity, following the manufacturers instructions